:)
Steps to Follow:
1)Start->Run->cmd
2)Type as Diskpart and Select Yes if a prompt Box appears
3)A new window will appear once you give Yes in the prompt Window
4)Type "list volume". This will list the available volumes along with letter and label of that drive
Suppose your "D drive" is "Volume 4". If u wanna make this disappear
5)Type "select volume 4"
6)Type "remove letter D"
Now You could find that D drive is no longer in Your My Computer !!!
To make it appear again:
Repeat the steps till 5
Instead of the command in 6) ,type "assign letter D"
U could find ur disk drive again in My computer. Screen shots of the Procedure can be seen